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Clinical practice

Ketamine-Assisted Psychotherapy

1,000+ treatments across three clinics since 2018. We combine ketamine with structured psychotherapy for treatment-resistant depression, PTSD, addiction, and eating disorders.

keynotepanelcliniciansacademicPolicy makers45 min + Q&A

Ketamine occupies a unique position in psychedelic medicine. It is the only psychedelic-class substance legally available for clinical use in most countries, yet it remains poorly understood by many practitioners and frequently reduced to its reputation as an anaesthetic or a party drug. I have administered over 5,000 ketamine treatments since 2016 and published research on its mechanisms, clinical applications, and phenomenology.

This talk explores ketamine's pharmacology as an NMDA antagonist, its relationship to classical psychedelics, and the growing evidence base for ketamine-assisted psychotherapy across depression, PTSD, addiction, and eating disorders. I address the dissociative experience directly: what patients report, what predicts therapeutic benefit, and how the subjective experience relates to clinical outcome.

Audiences range from psychiatrists encountering ketamine for the first time to experienced practitioners refining their protocols. I draw on both published research and clinical observation from Scandinavia's largest KAP practice.

Talks

7 Feb 2026 · Psychedelics as Medicine 2025 (Eden Foundation)

Ketamine: The Psychedelic Elephant in the Room

History, phenomenology, mechanisms and evolution of ketamine use in treatment of mental health disorders.

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24 Aug 2022 · Nordic Psychedelic Science Conference 2022 (NPSC)

Ketamine for the treatment of substance use disorders

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9 Nov 2023 · Wonderland Conference 2023 (Microdose)

Ketamine in a Therapeutic Setting as Treatment for Alcohol/Substance Use Disorder

Panel on using ketamine to treat substance use disorder.

13 Feb 2024 · Ketaminkonferansen 2024

Alle mann til pumpene! Dosering, titrering og vedlikehold

Practical session on ketamine dosing, titration and maintenance for physicians and leaders. Co-presented with Rupert McShane (University of Oxford).

Publications

2025clinical

Reconnecting through dissociation: a 5-month follow-up case study on ketamine-assisted psychotherapy for anorexia nervosa

Dahlgren CL, Tverrli E, Stewart LH
Journal of Eating Disorders, 13(1), 107
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2021clinical

Ketamin ved depresjon - evidens og forslag til praksis

Kvam TM, Stewart LH, Blomkvist AW, Andreassen OA
Tidsskrift for Den norske legeforening
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2018commentary

The dissociative psychedelic renaissance

Stewart LH
Journal of Psychedelic Studies
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2025peer-reviewed

Contextual and experiential aspects of the psychedelic experience predicting improvement in subjective wellbeing: results from a Norwegian internet convenience sample

Tunstad PA, Kvam TM, Uthaug MV, Stewart LH, Andersen KAA, Grønnerød C
Frontiers in Pharmacology, 16, 1556299
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2026peer-reviewed

MDMA-assisted therapy for major depressive disorder: A seven-month follow-up proof of principle trial

Kvam TM, Goksøyr IW, Rog J, van de Vooren IJ, Stewart LH, et al.
Journal of Psychiatric Research
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2026commentary

Clinical and non-clinical use of MDMA

Kvam TM, Goksøyr IW, Stewart LH, Berthold-Losleben M, Autran I, Andreassen OA
Tidsskrift for Den norske legeforening
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2025peer-reviewed

MDMA-assisted therapy as a treatment for major depressive disorder: proof of principle study

Kvam TM, Goksøyr IW, Rog J, van de Vooren IJ, Stewart LH, et al.
British Journal of Psychiatry
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2025clinical

Ketaminassistert psykoterapi for anorexia nervosa

Dahlgren CL, Tverrli E, Stewart LH
Tidsskrift for Norsk psykologforening
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2023clinical

Ketaminassistert psykoterapi for depresjon

Mølmen IF, Andersen K, Stewart LH, Castberg I
Tidsskrift for Norsk psykologforening
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2022peer-reviewed

Study protocol for "MDMA-assisted therapy as a treatment for major depressive disorder: A proof of principle study"

Kvam TM, Goksøyr IW, Stewart LH, Repantis D, Røssberg JI, Andreassen OA
Frontiers in Psychiatry, 13, 954388
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2024peer-reviewed

Exploration of MDMA-assisted therapy for major depressive disorder: a proof of principle study

Kvam TM, Goksøyr IW, Rog J, van de Vooren IJ, Stewart LH, Berthold-Losleben M, Mørch-Johnsen L, Andreassen OA
Neuroscience Applied, 3, 104179
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2020peer-reviewed

Sikkerhet og effekt av 3,4-methylendioksymetamfetamin (MDMA)-assistert psykoterapi ved posttraumatisk stresslidelse (PTSD)

Goksøyr I, Kvam TM, Lund-Høie S, Stewart LH
Tidsskrift for Norsk psykologforening, 57(12), 886-897
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